How do you test for cholestasis?
Diagnosis and Tests
A doctor diagnoses cholestasis of pregnancy with a physical examination and blood tests. These tests tell the doctor how the liver is functioning. They also measure the level of bile acids in the blood. Tests confirm the diagnosis when total bile acids measure 10 micromoles per liter and above.
How early can you detect cholestasis?
Symptoms of ICP typically start from around 30 weeks of pregnancy, but it’s possible to develop the condition as early as 8 weeks.
Can cholestasis go undetected?
Symptoms of intrahepatic cholestasis of pregnancy (ICP)
The cause in most of these cases remains unexplored. It is thought that the itching is caused in normal pregnancies due to the effect on the liver of high levels of hormones or even the stretching of the skin over the abdomen as the pregnancy progresses.
How does cholestasis feel?
Cholestasis of pregnancy usually starts with itching on the palms of the hand and the soles of the feet and then the itching begins to spread to other parts of the body, especially the belly.
Is delivery by 37 weeks necessary for cholestasis of pregnancy?
Given the increased risk of stillbirth in the setting of ICP, induction of labor is often recommended at 37 weeks of gestation to balance the risk of iatrogenic preterm delivery against the risk of fetal mortality.
How do you stop cholestasis itching?
To soothe intense itching, your pregnancy care provider may recommend:
- Taking a prescription drug called ursodiol (Actigall, Urso, Urso Forte), which helps to lower the level of bile in your blood. Other medications to relieve itching may also be an option.
- Soaking itchy areas in cool or lukewarm water.
Should I go to the hospital if I think I have cholestasis?
Call your doctor or nurse call line now or seek immediate medical care if: Your itching gets worse or you get other symptoms. You think that you are in labour. There is a new or increasing yellow colour to your skin or the whites of your eyes.
How common is stillbirth with cholestasis?
Compared to patients without ICP, those affected by ICP have a higher stillbirth rate. The stillbirth rate at 37 weeks’ gestation and beyond for the entire population in the United States is approximately 0.1% to 0.3% (1–3 per 1000).